Palladium-catalyzed tandem reaction of o-aminophenols, bromoalkynes and isocyanides to give 4-amine-benzo[b][1,4]oxazepines.

نویسندگان

  • Bifu Liu
  • Yibiao Li
  • Meizhou Yin
  • Wanqing Wu
  • Huanfeng Jiang
چکیده

A robust route to 4-amine-benzo[b][1,4]oxazepines relying upon a palladium-catalyzed tandem reaction of o-aminophenols, bromoalkynes and isocyanides has been developed. This chemistry presumably proceeds through the migratory insertion of isocyanides into the vinyl-palladium intermediate as a key step.

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عنوان ژورنال:
  • Chemical communications

دوره 48 93  شماره 

صفحات  -

تاریخ انتشار 2012